Lecture 19 Jan 2001 Per Kraulis

Sequence alignment: Pairwise and multiple

1. Sequence alignments: why?
2. Some definitions for sequence alignments
3. Algorithm for sequence alignments: dynamic programming
4. Database searching
5. Multiple sequence alignments: why?
6. An example of a multiple alignment
7. How to generate a multiple alignment?
8. Algorithmic complexity
9. A standard multiple alignment program: ClustalW
10. Databases of multiple alignments; domains

The 20 common amino acids, one-letter codes, formula, etc