GeneCV

Gene-centric data model for functional genomics

The events and transformations affecting a gene and its product from expression through function and to degradation

Gene
	Transcription	RNA polymerase
	Activation/silencing of transcription	Activators, repressors
mRNA
	Splicing, transport	Spliceosome
	Translation	Ribosome
Peptide
	Posttranslational modification	Enzymes
	Transport, folding
Protein	Complex, function, process, transport	Partners, enzymes, ligands
	Tagging, degradation	Enzymes

Issues in the description of molecular processes

• Chemical reactions, interactions
• Indirect interactions?
• Time, order
• Experiment vs. hypothesis
• Connection to physiology, cell biology