Formulation, simulation and analysis of biological systems using
mathematical models.
Goal
- Understand macroscopic biological phenomena in terms of
molecular mechanisms.
- Connect physiology and cell biology with molecular mechanisms in a
stricter way.
- Discover the organizing principles underlying biochemical networks.
Requirements
- Detailed descriptions of molecular mechanisms (reaction pathways)
- High-resolution data sets (functional genomics experiments)
Utility
- Perturbation analysis
- Hypotheses for roles of uncharacterized genes
- Analysis of robustness in a system
- Prediction of intervention points (medicine)