Lecture 12 Nov 2001, Per Kraulis

Multiple sequence alignments

1. Multiple sequence alignments: why?
2. An example of a multiple alignment
3. How to generate it?
4. Algorithmic complexity
5. A standard multiple alignment program: ClustalW
6. Databases of multiple alignments; domains

Chapters in the course book ("Introduction to bioinformatics", T K Attwood and D J Parry-Smith):

• Chapter 6, "Pairwise alignment techniques"
• Chapter 7, "Multiple sequence alignment"
• Chapter 8, "Secondary database searching"